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Enfin, les personnes atteintes dinsuffisance rnale svre ou dune maladie du foie avance doivent viter toute supplmentation non prescrite : ces organes jouent un rle important dans le mtabolisme et llimination de la vitamine, et leur fragilit peut modifier sa concentration sanguine

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The disease called beriberi (lack of vitamin B), which affects the nervous system and can cause weight loss, emotional disturbances, weakness, irregular heartbeats and more