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Furthermore, host-related factors, including age, sex, genetics, and physiological status, further modulate polyphenol metabolism, contributing to wide inter-individual differences in absorption and excretion
Seventy pathogenic variants in CPT2 gene were reported and phenotypegenotype association was observed in CPT2D (Joshi et al., 2014)
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Once TMAO formation/concentration is elevated, it may increase the risks of atherosclerosis for healthy individuals (48)
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