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Cardiovascular outcome trials have demonstrated that treatment with GLP1RA is linked to substantial cardiovascular benefits

This work was supported by the Health Commission of Hubei Province Scientific Research Project [HNJG-250005 (LL)], the National Science Foundation of Hubei Province [No

doi: 10.1007/s12035-022-03014-y

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FTY720 (fingolimod, GilenyaR, 2-amino-2[2-(4-octylphenyl)ethyl]-1,3-propanediol) is a structural analogue of S1P derived from myriocin, which acts as a pro-drug that must be phosphorylated by SK2 to be transformed into the active metabolite fingolimod-P