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So far only norharman and harman -carbolines have been reported in coffee (any reference in this review to -carbolines refers to only these two)

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Methylsulfonylmethane (MSM) is a sulfur-containing compound commonly found in diet and known to reduce oxidative stress

Co-immunoprecipitation mass spectrometry and CRISPR KO in cells identified that mitochondrial m -AAA protease AFG3L2 is responsible for degrading SLC25A39 through the matrix loop 1

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