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In industries, AGEs are used to improve flavor and color and increase the shelf life of food (30)

Abbreviations ER endoplasmic reticulum IMM inner mitochondrial membrane GCL glutamate-cysteine ligase GPx glutathione peroxidases GR glutathione reductase Grx Glutaredoxin GS glutathione synthetase GSH reduced glutathione GSSG oxidized glutathione GSH/GSSG ratio between reduced and oxidized glutathione GST glutathione S-transferase MOM mitochondrial outer membrane mtGSH mitochondrial glutathione OGC 2-oxoglutarate carrier ROS reactive oxygen species SLC soluble carrier protein TR thioredoxin reductase Trx Thioredoxin xCT cystine/glutamate antiporter SLC7A11 Footnotes Conflicts of interest J.W

J Biol Chem 1993, 268:1918819191

Two different clients, two appointments apart

doi: 10.1016/j.conb.2017.11.006 44 GreenbaumD.ColangeloC.WilliamsK.GersteinM

Front Med (Lausanne) 9 , 840752 (2022)