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The antioxidant response genes activated by NRF2 include genes responsible for (a) regulating GSH synthesis and metabolism, (b) antioxidant proteins like GPX, (c) drug-metabolizing enzymes and xenobiotic transporters, and (d) additional stress response proteins (Jaramillo and Zhang, 2013)
Therefore, the solid material recovered after acid pretreatment mostly consisted of cellulose and lignin, whereas hemicellulose comprised a relatively smaller portion of the carbohydrates in the treated material as compared to the untreated material (Xiao et al

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10.1126/science.7761837 92

Furthermore, both IGF-I and the IGF-IR are expressed in the developing glomerulus and patterns of expression are disrupted in animal models and in human examples of renal disease[140]