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National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention

Shandra, O

In the Golgi, SREBP- 2 is cleaved by proteases, releasing its active NH2-terminal domain, which translocated to the nucleus

Strikingly, this effect was entirely mitigated by treatment with Immunocal, which preserved neuronal viability to an extent similar to that of empty vector controls (Figure 7(b))

Pharmaceutics 14 , 404 (2022)

2 : 811820 Ichijo H, Nishida E, Irie K, ten Dijke P, Saitoh M, Moriguchi T, Takagi M, Matsumoto K, Miyazono K and Gotoh Y (1997) Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways