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Clinical signs include weight loss, polyphagia, polydipsia, hyperactivity, tachycardia, hypertension, and gastrointestinal disturbances such as vomiting and diarrhea
The recently published SYDNEY 2 trial showed significant improvement in neuropathic symptoms and neurologic deficits in 181 diabetic patients with 3 different doses of -Lipoic acid compared to placebo over a 5-week period 134
doi: 10.3233/JAD-191304 40 LinC

Nowak, Monika Udziela, Pawe Pitkiewicz, Iwona Grabska-Liberek, Jacek P
Department of Health & Human Services

Sidhu SS, Goyal O, Mishra BP, Sood A, Chhina RS, Soni RK
