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The compound regulates miRNA expression through AMPK signaling pathway activation and chromatin remodeling, with PDCD4 protein levels increasing by 60% following miR-21 inhibition (101)

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According to the EORS theory, aging is associated with sedentary behavior, which leads to an oxidized redox shift characterized by an extracellular decrease in the ratio of cysteine to cystine and an intracellular decrease in the ratio of GSH to GSSG and NAD(P)H to NAD(P) (419)