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Cells were collected at 0, 2, 4, 8, and 16 h after act-D treatment

doi: 10.1159/000119233 384 LawsonNHsiehCHMarchDWangX

Experiments conducted by Ahmed and colleagues have shown that pre-treatment of human chondrocytes with EGCG significantly prohibited the activities and expression of MMP-13 and MMP-1 (IC 50 values 16.5 and 27 mM, respectively) in vitro in a dose-dependent manner

It has been reported that NRF2 is significantly expressed in various malignancies and is closely linked to the malignant phenotype and patient prognosis [90]

10.3390/molecules26102999 22 DengY.YangL.AnS

The World Health Organization (WHO) and the Food and Agriculture Organization of the United Nations (FAO) suggest an intake of 34 g for adult men and 26 g for adult women