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High expression of HO-1 inhibits ferroptosis by reducing lipid peroxidation and ROS production

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Orekhov AN, Tertov VV, Mukhin DN, Mikhailenko IA (1989) Modification of low density lipoprotein by desialylation causes lipid accumulation in cultured cells: discovery of desialylated lipoprotein with altered cellular metabolism in the blood of atherosclerotic patients
GBM cells were seeded into 96-well plates at a density of 3000 cells per well and incubated for 0 h, 24 h, 48 h, and 72 h in a controlled environment at 37 C

Importantly, expression of both BDNF protein and specific BDNF mRNA isoforms are developmentally controlled, with different areas of the amygdala showing different expression patterns during adolescence and adulthood
