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To date, GST activity has been associated with resistance to all main classes of insecticides ( Classification Members of this family are classified according to their cellular localizations into three major families, i.e., cytosolic, mitochondrial/peroxisomal, and microsomal GSTs ( Wuchereria bancrofti was demonstrated ( Sigma Class Members of this class have been described in mammalians, chickens, insects, helminths, and mollusks ( Schistosoma hematobium antigen has been found to retain this enzymatic activity, and murine models have supported the concept that PGD2 production inhibits host immune response and favors parasite survival ( Mu Class Its members have a particular loop between the 2 sheet and the 2 helix, and they typically attach GSH to highly electrophilic compounds (28, 29)