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Since mouse microbiome profiles often highly correlate with body weight and fat composition, this study was designed to test whether the cecal microbiomes of DIO mice treated with NNMTi and LD were comparable to the microbiomes of age-matched lean counterparts and distinct from microbiomes of DIO mice maintained on a high-fat Western diet (WD) or subjected to LD switch alone

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By stimulating collagen synthesis and modulating fibroblast activity, it supports regenerative research protocols related to joint health, musculoskeletal recovery, and connective tissue maintenance

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Overall cellular energy production and mitochondrial health