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In hereditary or acquired metabolic defects, an initial intravenous bolus of 50 mg/kg may be administered over two to three minutes, followed by maintenance doses of 50 mg/kg every six hours or continuous infusion to achieve a total daily exposure of up to 300 mg/kg in critical illness

2016;48:e216

Riboflavin, Niacin (Vitamin B3) and Vitamin B6 all contribute to normal energy-yielding metabolism and reduction of tiredness and fatigue

( 10.1007/BF03261931) [DOI] [PubMed] [Google Scholar] Rowe PJ, Comhaire FH, Hargreave TB, Mahmoud AMA.2000

doi: 10.4103/1008-682X.153850
[DOI] [PMC free article] [PubMed] [Google Scholar] 85.Matalliotakis I., Koumantaki Y., Evageliou A., Matalliotakis G., Goumenou A., Koumantakis E
