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Heme synthesis is an eight-step reaction that takes place between the cytosol and the mitochondria (Fig

The enhanced bioactivity was attributed to phytochemical capping (terpenoids, alkaloids) and nanoscale surface interactions, which amplified ROS generation and membrane permeabilization in malignant cells ( Solanum trilobatum leaf extract to synthesize spherical AgNPs (20 nm) stabilized by polyphenolic ligands

Notably, the TFA-EB group exhibited the most pronounced reduction in kidney weight and kidney index, suggesting a synergistic therapeutic effect

Results Erucamide is downregulated during retinal degeneration Using high-resolution global mass spectrometry-based metabolomics, we cataloged the metabolites dysregulated during retinal degeneration in an animal model of RPE-mediated retinal degeneration, the Royal College of Surgeons (RCS) rat