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The primers for constructing the plasmids are listed in Table EV1

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Author contributions C.S

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Abd El-Fattah EE

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George MM, Subramanian Vignesh K, Landero Figueroa JA, Caruso JA, Deepe GS Jr

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Safety Measurements Any adverse event during the course of the study was monitored and reported to the study staff at week 6 (visit 5) or week 12 (visit 8) in the clinic or directly to the principal investigator throughout the study

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Those KEAP1-binding competitors, such as p21 Cip1/WAF1 and BRCA1, were found interacting with NRF2 and thus block the association of KEAP1 with NRF2 [18, 19]

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