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Most Americans have some degree of gut compromise from processed food, antibiotic history, chronic stress, or environmental toxins

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While traditional joint supplements like glucosamine and turmeric have dominated for years, newer solutions such as oral peptide compounds are now stepping into the spotlight

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The mammalian sirtuins (Sirt1--Sirt7) participate in a number of cellular and physiological functions such as gene silencing, apoptosis, mitochondrial function, energy homeostasis, and longevity [237].Transgenic mice with overexpression of the sirt1 gene demonstrate decreased lipid-induced inflammation, improved glucose tolerance, and protection from hepatic steatosis when fed a high-fat diet [238]