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This effect was evidenced by improved uptake of soluble antigens, elevated expression of genes encoding IL-6, TNF-, iNOS, and IL-1, and a marked increase in nitric oxide production (223, 224)

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This is an enzyme that uses glutathione to lower oxidative damage in tissues, so selenium indirectly affects the antioxidative action of glutathione

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Oxidative reactions primarily target lipids, particularly polyunsaturated fatty acids (PUFAs), which is a major problem for both natural and processed foods