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Cell Chem Biol 27:420435

Relationships of HAEC gene expression with BAL fluid ( n = 84) and intracellular ( n = 23) GSH pathways Altered redox balance ex vivo correlates with worsened clinical and physiologic outcomes BAL fluid

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For gliogenesis (Figure 8B), genes that were downregulated in both the 10 and 100 ng/mL TNF- suggest a shift in the state of astrocytes, in particular the role of astrocyte differentiation (e.g., SOX6, SOX8, SOX9, VIM, VAX1, DRD1, FGFR3, PLP1, NOTCH1 and NR2E1 ), and glial cell migration (e.g., VIM, NTN1, EFEMP1, ATP1B2, DOCK8, PTPRZ1, GLI3, FOXG1 , and NR2E1 )

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