glutathione reduced for connective tissue disease Role of in Cancer: From Mechanisms to Therapies The Importance of Glutathione in
Description
Methods Enzymol (2015) 559:115
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Although antioxidants may save normal cells from oxidative harm, excessive antioxidant activity may disrupt therapeutic lipid peroxidation, diminishing the effectiveness of therapies that use this process to target cancer cells
The combination of the GSTM1 null and GSTT1 null genotypes resulted in an age-adjusted odds ratio of 1.1 (95% CI 0.62.0), compared with the GSTM1 positive and GSTT1 positive genotypes
Mechanical shear can disrupt the disulphide bond and destabilise the loop conformation
