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In human small cell lung cancer cell lines - H69 and H345 which have functional c-Met receptor, SU11274 inhibits the HGF-induced cell growth with the IC 50 of 3.4 M and 6.5 M, respectively

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2023;18(4) doi: 10.1088/1748-605X/acce88

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The authors reported that addition of Epitalon to cultures of telomerase-negative human fetal fibroblasts induced expression of the telomerase catalytic subunit (hTERT), increased telomerase enzymatic activity by TRAP assay, and was associated with telomere elongation across the culture period