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Reactive oxygen species can attack biomembranes, enzymes, proteins, and nucleic acids (Venditti et al., 2013)

The duration of semaglutide treatment varies, but most patients remain on the medication long-term since discontinuation typically leads to weight regain

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Moreover, it was observed that the intracellular Fe 2+ level increased in TBH-treated ARPE-19 cells but that there was no significant change in Fe 2+ after pretreatment with FER-1 or deferoxamine (DFO) (46)