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Arguably, the substances involved in this context choline, betaine, vitamin B6, vitamin B12 (methylcobalamin), folate (methyl-THF) and SAM all have a much more direct connection to the symptoms attributed to homocysteine and are therefore often the root cause of a disease

Studied primarily for tissue repair, angiogenic effects, and growth factor signaling

The sourcing risk still applies

Vitamin B12 deficiency symptoms The most common vitamin B12 deficiency symptoms include (2, 11): Pale skin Low energy Shortness of breath Palpitations Tingling or numbness in hands and/or feet Lower sense of position of body parts Lower ability to feel vibrations Abnormal walking pattern Muscle weakness Loss of concentration Poor memory Confusion Depression Vision problems Insomnia Impotency Poor bowel or bladder control Constipation Flatulence Sore tongue Appetite loss Loss of mental or physical drive Can I have a vitamin B12 deficiency without any symptoms

It binds to collagen fibrils and controls how they assemble into larger fibers

June 07, 2024 Oral B-12 vs Injection section of our B Vitamin Supplements Review, which includes our Top Pick for high-dose B-12