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Ferroptosis suppressor protein 1 (FSP1), originally identified as apoptosis-inducing factor mitochondria-associated 2 (AIFM2), was rediscovered through unbiased genetic screens as a potent GPX4-independent ferroptosis inhibitor (96)

Loss of p53 function through mutation results in profound metabolic reprogramming

Uses: Diazepam, alprazolam, lorazepam overdose

It protects brain mitochondria from oxidative stress and recycles other antioxidants, such as vitamins C and E

For example, certain alkyl phospholipid oxidation products in oxidized lowdensity lipoprotein are highaffinity extracellular ligands for peroxisome proliferatoractivated receptor (PPAR) that induce PPARresponsive genes [116]

We have already talked about the benefits of collagen in the skin cells