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When a full blood count reveals macrocytosis (enlarged red blood cells, indicated by a raised MCV), this should prompt investigation for B12 or folate deficiency before relying on HbA1c for diabetes management decisions

In the resting liver, a balance between matrix synthesis and degradation exists, whereas, in the injured liver, the balance is disrupted

To simulate hypoxia condition, cells were cultured in presence of 100 M Cobalt(II) chloride hexahydrate (CoCl 2 .6H 2 O, Sigma Aldrich) for 24 h

Palacios-Filardo and Mellor, 2019)

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Dr Eron Horchik pinpointed the root cause using a quick visual scapula assessment