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However, when similar degrees of differentiation were accounted for, by aligning differentiating colonies from the termianl differentiation division (TD) and working backwards, we found that the likelihood of a DD division increased over the preterminal divisions, from 0 to 20% at F-5 to 100% at terminal differentiation

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Examples include tryptases recruiting inflammatory cells into the lungs, neutrophil elastase inactivating tissue inhibitors of metalloproteinases, MMPs inactivating alpha-1 antitrypsin and macrophage inflammatory protein-1