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Specific dosing parameters vary significantly between studies and animal models researchers should reference the primary literature for protocol design

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At least a 25% decrease in negative/disorganization symptoms, including excitement (excitement, hostility, tension, grandiosity, and uncooperativeness), depression (depressive mood, guilt feelings, and motor retardation) and positive symptoms (unusual thought content, suspiciousness, and hallucinatory behavior) were observed between the first and last visits

Treatment options range from non-hormonal and hormonal medical awareness to surgical procedures, depending on the patients symptoms and goals

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