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23 GaoC.CatucciG.GilardiG.SadeghiS

While p53 arrests the cell cycle in response to cellular stress and DNA damage, p27 and p21 inhibit cyclin-dependent kinases, thereby blocking proliferation and enforcing cell-cycle arrest.31,39,40 Second, a high p38/ERK low activity ratio favors dormancy

Am J Physiol 1991

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10.1001/jama.290.7.912 61
Han HC, Parsons SA, Teh AW, Sanders P, Neil C, Leong T, et al
