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These trials included both single-dose pharmacokinetic studies and long-term efficacy trials extending up to 24 weeks of continuous administration

This mechanism is sometimes described separately from the angiogenic pathway because it appears to involve protective signalling at the mucosal layer rather than vascularisation per se though the two are not mutually exclusive in research protocols

Intramuscular B12 injections : Recommended for individuals with absorption issues or severe deficiency

Medicine 101 , e28896 (2022)

[DOI] [PubMed] [Google Scholar] 75.OSullivan S.S., Williams D.R., Gallagher D.A., Massey L.A., Silveira-Moriyama L., Lees A.J

doi: 10.1016/j.transproceed.2010.02.097