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The model proposes that Keap1 binds Nrf2 initially through the high-affinity ETGE motif, followed by docking of the low-affinity DLG motif onto the -propeller of the adjacent Keap1 molecule

Glutathione is the master antioxidant that reduces free radicals

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When antigens from food, bacteria, or toxins come into contact with mast cells, the cells release mediators that cause various physiological responses, including inflammation

doi: 10.1016/j.freeradbiomed.2007.10.054

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