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The mechanism involves regulation of ferroptosis-associated proteins and the miR-429/SLC7A11 pathway

Azelaic Acid Azelaic acid, or 9-carbonodicarboxilic acid, is a nonphenolic compound derived from the yeast Pityrosporum ovale

All of these transcriptional effects collectively create a TME optimal for glioma expansion, not only by fueling metabolic needs but also by orchestrating the structural and immunological landscape around the tumor allowing it to thrive ( Figure 4 )

While research is promising, its not yet FDA-approved, so its often used off-label or in research settings

Marzatico F1, Pansarasa O, Bertorelli L, Somenzini L, Della Valle G

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