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GPX4, the master regulator of lipid peroxidation detoxification, is overexpressed in glioblastoma [10, 11], making it a prime therapeutic target

Yu D, Yang P, Lu X, Huang S, Liu L, Fan X

Available from: Greco A, Gallo A, Fusconi M, Marinelli C, Macri GF, De Vincentiis M

To this end, we induced ferroptosis with RSL3 and measured LPO using BODIPY-C11 and coumarin hydrazide (CHH)

Mechanical forces trigger primary cell death, cellular lysis and cytotoxic oedema

2008 The cardioprotective action of andrographolide was also completely abolished by buthionine sulfoximine, which acts as a specific gamma-glutamate cysteine ligase (GCL) inhibitor to deplete cellular GSH level