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In addition to its structural role, rewired phospholipid metabolism generates diverse bioactive molecules involved in oncogenic signal transduction, such as lysophosphatidylserine [42] and phosphatidic acid [43]

Further, the expression of Pdk1 , Pdk2 , and Pdk4 , the kinases that phosphorylate and inhibit pyruvate dehydrogenase, the rate-limiting enzyme of glucose oxidation, was significantly decreased in SKM of clenbuterol-treated mice (Fig

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