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Further demonstrating the therapeutic potential of targeting glycolysis, the natural compound derivative D5, sourced from Radix Aucklandiae, attenuates colitis in mice by impeding the nuclear translocation of PKM2 dimers, thereby suppressing glycolytic flux and Th17 cell differentiation (211)

Impact of marrow complete response in the natural history of patients with myelodysplastic syndromes (MDS) and chronic myelomonocytic leukemia (CMML) treated with hypomethylating agents

J Neurosci 34(32):1062434 Brookes PS, Yoon Y, Robotham JL et al (2004) Calcium, ATP, and ROS: a mitochondrial love-hate triangle [J]

Levothyroxine should be taken on an empty stomach, typically 30 to 60 minutes before breakfast, to ensure optimal absorption

doi: 10.1016/0304-4165(76)90029-5

Notably, individuals carrying the HLA-B * 35:01 allelefound in 1015% of the populationappear to be genetically predisposed to curcumin-induced liver injury