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10.1016/j.plantsci.2011.03.019 4 Arasimowicz-JelonekM.Floryszak-WieczorekJ.KosmalaA

The demonstrated importance of protecting the terminals to pharmacokinetic characteristics suggests numerous additional synthetic approaches that may be applicable including the insertion of non-peptide linkages between the first and second amino acids, the replacement of the N~terminal amino acid with a non-a amino acid, and N-terminal acylation

This method allows for direct absorption into the bloodstream, potentially leading to quicker effects

Apply a small amount to a discrete area, wait 24 to 48 hours, and check for reaction before proceeding with scalp application