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In psychiatric disorders, abnormalities of melatonin secretion and regulation have been reported [7, 8]

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Glutathione S -transferases M11 and T11 as risk modifiers for renal cell cancer associated with occupational exposure to chemicals

[13] Chloramphenicol has been shown to blunt reticulocyte response to cyanocobalamin, while ethanol, colchicine, and nitrous oxide interfere with cobalamin metabolism or utilization, each warranting clinician awareness when evaluating suboptimal treatment outcomes

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