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Additionally, plant metabolites and derivatives can regulate ferroptosis by targeting SLC7A11, GPX4, and ACSL4 and influence the immune status in the tumor microenvironment, providing new insights and directions for TCMs in cancer treatment

doi: 10.3390/nu12103138

Healthcare Provider Awareness If you use DSIP or plan to, informing your healthcare provider allows them to consider this in your overall care picture

GeroScience 45 , 2943 (2023)

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By means of processes like stimulating Treg cell proliferation and encouraging the transformation of M0-type macrophages into M2-type, IDO creates an immunosuppressive milieu in the TME that facilitates tumor evasion of immune surveillance ( IDO1 plays a key role in immune escape in AML, but targeted therapy is still in the early stage of exploration