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(Figure 5.20) 5.3 Phase II Metabolism Whereas Phase I is largely focussed on oxidases that aim to introduce a polar functional group, Phase II involves transferases that conjugate a biomolecule onto the drug

All cells were tested for mycoplasma contamination and utilized before 20 passages and treated in the exponential growth phase at ~70% confluence

Flux balance analysis simulates steady-state flux values through the networks reactions and predicts the reactions needed to maximize the objective function, which was selected as the biomass equation

38 In line with these results, our study also found that patients who died had significantly higher rates of HT (75.0% vs