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Funding This work was supported by the Tabriz University of Medical Sciences [72742]

However, ROS are also critical to the induction of antitumor immunity.15 This complexity in the effects of ROS should help explain the controversial observations that dietary antioxidant supplementation can promote tumor progression and metastasis.4 6 Here we summarize ROS production, redox regulation and the contributions of ROS to immune responses under physiological conditions

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Iron in infection and immunity