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Description
Replication was attenuated by D1467G but constantly increased, reaching comparable levels to wt at 72 and 96 h
Funding This study was unfunded
Observational studies have found eating and drinking close to bedtime was correlated with increased wakefulness and increased chance of abnormal (short or long) sleep duration
A.TigueZ
The sequence begins with progesterone, which is converted to 17-hydroxyprogesterone by CYP17A1, then to 11-deoxycortisol by CYP21A2, and finally to cortisol by CYP11B1
N Engl J Med 2019;380:1122.ArticlePubMed 67
