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Description
High-fat diet-induced lysosomal dysfunction and impaired autophagic flux contribute to lipotoxicity in the kidney

An interference with carnitine transport occurs in tissues, including renal reabsorption, which explains the low plasma and tissue levels in these patients

Because BCAAs, such as valine, leucine, and isoleucine, are absorbed in the peripheral tissue, patients with cirrhosis have a lower concentration of the BCAAs and a higher concentration of the aromatic amino acids in the blood compared with healthy people

2013 2595 - -N- (TMAO)

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Mosharov EV, et al
