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- glucans maintain the balance of blood glucose and cardiovascular diseases (16), enhance the immune system (17) and wound healing activities (18), and show antimicrobial (antibacterial and antiviral) properties (Figure 1)
Accumulated ROS under pathological conditions-such as inflammation, ischemia, or denervation-activate upstream kinases (ASK1, MKK3/6, MKK4/7), leading to p38 and JNK phosphorylation
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