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This rare autosomal recessive genetic disorder caused by DPP1 gene (CTSC) mutations occurs with an incidence of approximately 1-4 per million (Toomes et al., 1999)

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Therefore, electron microscopy is considered essential in the diagnostic work-up of pediatric liver biopsies, given that ultrastructural mitochondrial abnormalities help to distinguish WD from NAFLD and autoimmune hepatitis [28]

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Without her, I dont think I would have stayed with the route