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Estrogen receptor beta-dependent Notch1 activation protects vascular endothelium against tumor necrosis factor alpha (TNFalpha)-induced apoptosis
2022 Jul 25:1-22

Synaptic dysfunction is a major feature of many neurodegenerative diseases, including AD (Jackson et al., 2019)

Maintenance dose is 280 mg/day

We demonstrated that our approach added increased value to established biomarkers of AD, and we expect that multimodal aging and disease prediction models may have similar impacts in other diseases