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683 Intermittent fasting (IF) has been reported to reduce lipid peroxidation and mitochondrial dysfunction, and one month of IF increased the expression of protective GPX4, partially eliminated the ferroptosis of cortical neurons induced by TBI, and helped to alleviate cognitive impairment

38 Iron overload Although iron is a helpful component of the human body and the major micronutrient in the human diet, involved in crucial cellular functions and metabolic processes, excessive iron increases the production of ROS, leading to cell dysfunction or death, tissue damage, and organ disease

doi: 10.1007/s11011-022-01074-6 132 YangJKYangJPTongJJingSYFanBWangFet al