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927 These results suggest that HDAC3 maintains iron homeostasis through the Hippo/YAP pathway and might represent a target to reduce ferroptosis in iron overload-related diseases

Nat Rev Drug Discov 16:487511

SARS CoV-1 enhances the expression of TGF-1, leading to elevated ROS, depletion of glutathione, and decreased levels of the substrates and enzymes required for glutathione synthesis

Wang H, Zhou Y, Zhuang W, et al

Perspectives and conclusions As discussed above, intracellular ROS homeostasis is a fundamental aspect of cell physiology