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Consequently, iron chelation is likely to be beneficial only when ferroptosis is the primary driver of neurodegeneration and when the initiating event is an excess of labile iron driving Fenton chemistry and lipid peroxidation

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G., et al

The Wnt/beta-catenin pathway is one of the most conserved signaling systems in human biology

Lanicemine: a low-trapping NMDA channel blocker produces sustained antidepressant efficacy with minimal psychotomimetic adverse effects