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In preclinical studies, administration of MOTS-c improved muscle performance and physical capacity in the absence of structured exercise, suggesting potential relevance for aging or mobility-restricted populations (Lu H et al., 2019)

Without enough, we can get anemia and other serious health problems

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, Ehring T., Braendle M., and Schelling P

This enhanced scrutiny helps paint a clearer, more granular picture of its effects

When CD47 binds to SIRP on dendritic cells and macrophages, it activates an immunoreceptor tyrosine-based inhibitory motif that suppresses phagocytosis (61)