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HGF/c-Met, EpCAM cross talk in PI3K/Akt/mTOR It is well established that the c-Met/PI3K/Akt signaling axis is crucial to regulate tumor cell critical functions, such as proliferation and survival

After 3 and 5 min the HPLC profile for complex 3 showed two signals

The gap between choosing the right compound and wasting months on protocols that don't match the biological question comes down to understanding what each molecule actually does at the receptor level

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Theranostics 10(11):51075119 Cheng ZJ, Miao DL, Su QY et al (2019) THZ1 suppresses human non-small-cell lung cancer cells in vitro through interference with cancer metabolism