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It is also important to address the underlying trigger when managing this type of acne

J Physiol 536(Pt 3):741751 Christofi FL, Wunderlich J, Yu JG, Wang YZ, Xue J, Guzman J, Javed N, Cooke H (2004) Mechanically evoked reflex electrogenic chloride secretion in rat distal colon is triggered by endogenous nucleotides acting at P2Y1, P2Y2, and P2Y4 receptors

The fluorescent labeling of these cells demonstrated the presence of initial apoptosis, subsequent apoptosis, and additional necrosis indicators, and their increase with contact extension (Sharaf et al., 2024b)